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Meanings and definitions for SH2

Silent Hill 2, a 2001 survival horror video game published by Konami
SH2 domain (Src Homology 2), a protein domain within the Src oncoprotein
SH-2, an iteration of the SuperH CPU core developed by Hitachi
SH-2 Seasprite, an American-built ship-based helicopter
SH-2G Super Seasprite, an American-built ship-based helicopter
Shadow Hearts: Covenant, also known as Shadow Hearts II
State Highway 2, see List of highways numbered 2, a common highway name in many countries
Hydrogen sulfide
SH2, one of three classifications of participants in Paralympic shooting events