MCSP can refer to:
Canada/USA Mathcamp
Merlin Capability Sustainment Plus: Mid-Life Update of Merlin (see Lockheed Martin U.K. and AgustaWestland EH101)
Melanoma-associated chondroitin sulfate proteoglycan, a tumour marker
Member of the Chartered Society of Physiotherapy
Minimum cost spanning tree, the lowest costing way to construct a spanning tree graph.